Award
NIH Reporter #5R35GM124633-10
Elucidating the regulation and function of amyloid-like assemblies
Recipient
Columbia University Health Sciences, New York, NY, United States
Award Amount
$449,473.00
Ceiling
$449,473.00
Awarded
August 14, 2026
Identifier
5R35GM124633-10
This award supports research on the regulation and function of amyloid-like assemblies using yeast models to understand molecular mechanisms, aiming to provide insights into neurodegenerative diseases and potential therapeutic strategies.
Description
Research to delineate the physiological pathways and mechanisms that healthy cells have evolved to regulate formation, function, and reversibility of amyloids, focusing on yeast models to understand molecular mechanisms underlying amyloid assembly and disassembly with implications for neurodegenerative diseases.