Award
NIH Reporter #11384505
Validation of an aqueous humor liquid biopsy for molecular prognostication and monitoring of children with retinoblastoma.
Recipient
Children's Hospital of Los Angeles
Award Amount
$561,836.00
Ceiling
$561,836.00
Awarded
August 11, 2026
Identifier
11384505
Award for a multi-center study validating aqueous humor liquid biopsy to improve diagnosis and prognosis in children with retinoblastoma, supporting eye salvage treatment decisions.
Description
The project involves liquid biopsy of eye aqueous humor for molecular characterization and prognostic biomarker validation in retinoblastoma. The study aims to inform diagnosis and prognosis for eye salvage based on genomic and epigenomic biomarkers. It is a multi-center, multi-omics, prospective study that benefits include advancing knowledge, guiding treatment, and future clinical trials.