Award

National Eye Institute 5R01EY034990-05

Correlating the microstructural thickness variations of the tear film lipid layer with clinical characteristics of dry eye with a novel optical method

Recipient

University of South Florida, Tampa, FL

Award Amount

$374,877.00

Ceiling

$374,877.00

Awarded

June 05, 2026

Identifier

5R01EY034990-05

This award funds research to study the tear film lipid layer thickness variations and their link to dry eye disease using a novel optical method, aiming to improve non-invasive assessment of the disease.

Description

Project focuses on characterizing microstructural thickness variations of the tear film lipid layer (TFLL) and their association with clinical characteristics of dry eye disease (DED). Utilizes a novel laser source point-scanning interferometer for in vivo assessment. Aims to verify the inverse relationship between TFLL thickness and tear film evaporation rate. Seeks to develop parameters for non-invasive assessment of DED. Funded by NIH/NEI under grant PA-20-185. Project duration: May 1, 2023, to April 30, 2028.

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