Award

National Eye Institute 2R01EY031696-06

Innate and Adaptive Immunity in the Pathogenesis of Glaucoma

Recipient

Schepens Eye Research Institute

Award Amount

$834,935.00

Ceiling

$834,935.00

Awarded

June 23, 2026

Identifier

2R01EY031696-06

This NIH grant supports research on the immunological mechanisms underlying glaucoma, specifically the role of microglia and T cells in neuroinflammation and the potential therapeutic role of IGFBPL1.

Description

Research grant focused on understanding how microglia, T cells, and their interactions contribute to neuroinflammation and retinal ganglion cell loss in glaucoma, investigating the role of IGFBPL1 as an immunological checkpoint ligand to modulate neuroinflammation and potentially develop targeted therapies.

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