National Institute of Biomedical Imaging and Bioengineering 5R21EB034457-03

Investigating the effect of mechanical compliance of metamaterial interbody cages on spinal fusion progress in vivo

NIH awarded a grant to the University of Pittsburgh to study how the mechanical compliance of metamaterial interbody cages affects spinal fusion progress in vivo, using sheep models to compare stiff and compliant cage designs.

Description

This NIH grant project aims to investigate the relationships between the compliance of interbody metamaterial fusion cages, load-sharing, and spinal fusion progression in vivo. The study involves designing compliant metamaterial orthopedic implants and fixation devices, testing them in sheep cervical spine models, and comparing fusion rates between stiff and compliant cages.

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