Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK039773-39
Mechanisms of Ischemic Kidney Injury and Repair
Recipient
Brigham and Women's Hospital, Boston, MA, United States
Award Amount
$712,313.00
Ceiling
$712,313.00
Awarded
December 15, 2025
Identifier
5R01DK039773-39
Research project funded to study mechanisms of kidney injury and repair, focusing on DNA damage and fibrosis to develop treatments for acute kidney injury.
Description
The studies aim to understand the mechanisms involved in kidney cell injury and repair to develop therapeutic strategies for prevention and treatment of acute kidney injury (AKI) and its chronic consequences. The research focuses on DNA damage responses, cell cycle arrest, senescence, and fibrosis pathways using animal models and human cell systems.