Award
National Institute of Allergy and Infectious Diseases 1R21AI196587-01
Characterizing NLRP11 Activation by Mycobacteria to Enhance Innate Immune Responses
Recipient
University of Maryland, College Park
Award Amount
$421,720.00
Ceiling
$421,720.00
Awarded
February 02, 2026
Identifier
1R21AI196587-01
Research project funded by NIAID to study how the NLRP11 inflammasome recognizes mycobacteria, potentially improving tuberculosis vaccines.
Description
The project aims to understand the recognition mechanisms of mycobacteria by the NLRP11 inflammasome. The research involves screening mycobacterial species and subcellular fractions, and identifying genes encoding ligands. The project could lead to improved tuberculosis vaccines.