Award
National Heart, Lung, and Blood Institute 5R01HL103920-14
Role of integrin a5b1 in vascular patterning and the formation of the pharyngeal arch arteries
Recipient
Rutgers Biomedical and Health Sciences, Newark, NJ, United States
Award Amount
$436,807.00
Ceiling
$436,807.00
Awarded
August 23, 2024
Identifier
5R01HL103920-14
A research project funded by the National Heart Lung and Blood Institute to study the role of integrin a5b1 in vascular patterning and pharyngeal arch artery formation, aiming to understand congenital heart disease mechanisms.
Description
This project investigates the role of integrin a5b1 and Fn1 in the development of the pharyngeal arch arteries, which are critical for proper cardiovascular formation. The research aims to understand the genetic and cellular mechanisms regulating the formation and remodeling of the 4th pharyngeal arch artery, defects of which cause severe congenital heart disease.