Award
National Institute of Neurological Disorders and Stroke 5R01NS124889-05
Synergistic Enhancement of Peripheral Nerve Defect Repair using Peptide Functionalized Aligned Nanofiber Conduits
Recipient
Duke University
Award Amount
$423,545.00
Ceiling
$423,545.00
Awarded
June 03, 2026
Identifier
5R01NS124889-05
The award supports research to improve peripheral nerve repair by using peptide-functionalized aligned nanofiber conduits to enhance Schwann cell infiltration and nerve regeneration, combining topographical and biochemical cues in a rat model.
Description
This project aims to develop peptide-functionalized nanofiber conduits to enhance nerve regeneration, focusing on Schwann cell infiltration and functional recovery in a rat model. The project includes in vitro optimization and in vivo validation, with a multidisciplinary approach involving biomaterials, neurobiology, and regenerative medicine.