Award
National Institute of Neurological Disorders and Stroke 5R01NS126342-03
The Impact of Beta- and Gamma-Synucleins on Alpha-Synuclein's Synaptic Function
Recipient
WEILL MEDICAL COLL OF CORNELL UNIV
Award Amount
$754,960.00
Ceiling
$754,960.00
Awarded
May 07, 2026
Identifier
5R01NS126342-03
Research project awarded to study the impact of beta- and gamma-synucleins on alpha-synuclein's synaptic function, aiming to understand their roles in neurodegenerative diseases and develop new therapies.
Description
The project involves studying the effects of beta- and gamma-synucleins on alpha-synuclein's synaptic function to clarify the roles of different synucleins in neurodegenerative diseases such as Parkinson’s disease and Lewy body dementia. The research emphasizes multidisciplinary approaches including biophysical, biochemical, electrophysiological, and animal studies and may contribute to developing new therapeutic strategies targeting all synucleins.