Award
NIH Reporter #4R01MH134803-02
Scalable high-plex pipeline for whole-brain proteomics profiling
Recipient
University of Michigan at Ann Arbor
Award Amount
$3,061,628.00
Ceiling
$3,061,628.00
Awarded
September 07, 2026
Identifier
4R01MH134803-02
The award funds the development of a high-throughput proteomics pipeline to profile the whole mouse brain proteome across six postnatal stages, improving multiplexity, acquisition speed, and data storage efficiency.
Description
This project aims to develop a scalable, high-throughput proteomics pipeline using a 100-plex antibody panel, an ultra-speed light-sheet microscope, and advanced data compression to map the proteome of the mouse brain across developmental stages.