Award
National Institute on Drug Abuse 1R21DA062805-01
Temporal interference methods for addiction treatment
Recipient
TRUSTEES OF INDIANA UNIVERSITY
Award Amount
$420,519.00
Ceiling
$420,519.00
Awarded
July 08, 2025
Identifier
1R21DA062805-01
This award funds a clinical trial to evaluate temporal interference electrical neurostimulation as a non-invasive treatment for addiction, focusing on nicotine craving and use reduction.
Description
The project aims to test non-invasive electrical neurostimulation (temporal interference) for addiction treatment, specifically targeting nicotine craving and use. It involves a preliminary clinical trial with heavy smokers and vape users, randomized into groups receiving stimulation to the nucleus accumbens, anterior insula, or sham control. The study measures craving, vapor inhalation, cognitive abilities, emotion, motivation, safety, and tolerability.