Award
National Institute of General Medical Sciences 5R35GM147414-05
The Molecular Basis for Integrin-Mediated Bidirectional Signaling
Recipient
Fred Hutchinson Cancer Center
Award Amount
$440,000.00
Ceiling
$440,000.00
Awarded
June 30, 2026
Identifier
5R35GM147414-05
Award for research on integrin-mediated signaling to aid therapeutic design for autoimmune diseases.
Description
Research project to decipher the molecular basis for β2 integrin activation, ligand recognition, and bidirectional signaling using cryoEM, membrane mimetic systems, and mutational analysis to provide a structural blueprint for the rational design of therapeutics for autoimmune diseases.