Award
NIH Reporter #1ZIADE000758-05
Metabolic Bone Disorders Unit
Recipient
National Institute of Dental & Craniofacial Research
Award Amount
$2,314,275.00
Ceiling
$2,314,275.00
Awarded
January 01, 2025
Identifier
1ZIADE000758-05
A research project funded by the National Institute of Dental and Craniofacial Research studying metabolic bone disorders, particularly fibrous dysplasia/McCune-Albright syndrome, focusing on fracture risk, craniofacial development, and treatment strategies.
Description
Research project focusing on craniofacial and associated skeletal disorders, using fibrous dysplasia/McCune-Albright syndrome (FD/MAS) as a model to study pathogenesis and treatment. The project investigates fracture risk, management, prevention, and developmental craniofacial disorders, with specific aims for FY2025 including characterizing FD/MAS natural history, studying osteoclasts' role, and investigating FGF23 excess as a driver of skeletal morbidity.