Award
National Institute of Mental Health 5R21MH136576-02
A microphysiological model of the neurovascular unit capable of demonstrating neurovascular coupling
Recipient
Vanderbilt University
Award Amount
$188,270.00
Ceiling
$188,270.00
Awarded
February 20, 2026
Identifier
5R21MH136576-02
Development of a human neurovascular unit model to study neurovascular coupling and test therapies for cognitive impairments.
Description
The project aims to develop a human neurovascular unit (NVU) model that can demonstrate neurovascular coupling (NVC). The model will incorporate contractile cells responsive to biochemical signals, enabling studies of NVC in health and disease, and testing potential therapies.