Award
Eunice Kennedy Shriver National Institute of Child Health and Human Development 5F31HD113285-02
Dissecting the role of ZCWPW1 in oocyte quality, fertility and ovarian physiology.
Recipient
University of Michigan at Ann Arbor, MI
Award Amount
$43,588.00
Ceiling
$43,588.00
Awarded
July 18, 2025
Identifier
5F31HD113285-02
The award supports research on the role of the protein ZCWPW1 in female meiosis and ovarian physiology, investigating its impact on oocyte quality and fertility using genetic and molecular methods.
Description
This project aims to examine the role of ZCWPW1 in female meiosis, focusing on homolog pairing, recombination, meiotic prophase progression, and oocyte elimination or survival. The study uses genetic models and molecular techniques to provide insights into female meiotic chromosome dynamics and the role of ZCWPW1 in oocyte quality control and ovarian reserve establishment and maintenance.