Award

National Institute of Arthritis and Musculoskeletal and Skin Diseases PA-25-301

Molecular Mechanism of Human Myogenesis

Recipient

University of Georgia, Athens, GA

Award Amount

$614,390.00

Ceiling

$614,390.00

Awarded

May 01, 2026

Identifier

PA-25-301

NIH funded research project to study CHAMP1 gene's role in muscle development and disease, aiming to develop therapies for CHAMP1 syndrome muscle symptoms.

Description

This NIH grant project aims to elucidate the role of CHAMP1 in muscle development and disease, identify key molecular targets, and develop new strategies to treat muscle symptoms associated with CHAMP1 syndrome. The project involves in vivo mouse models, spatial transcriptomics, biochemical mechanism studies, structural modeling, and gene therapy testing.

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