Award
National Institute of General Medical Sciences 2R35GM136233-06
Genetic and Molecular Dissection of Wnt Pathway Activation
Recipient
Dartmouth College
Award Amount
$627,840.00
Ceiling
$627,840.00
Awarded
July 11, 2025
Identifier
2R35GM136233-06
Research project funded by NIH to study Wnt signaling mechanisms and develop therapeutic strategies for Wnt-driven diseases using genetic, biochemical, and proteomic methods.
Description
This project aims to elucidate the mechanisms of Wnt pathway activation, focusing on the regulation of key protein complexes and kinases involved in Wnt signaling. The research employs advanced genetic, biochemical, and proteomic techniques, with collaborations across multiple experimental approaches to develop therapeutic strategies for Wnt-driven diseases.