Award
NIH Reporter #1F31AI200278-01
Investigating the role of ITK in tuning CD8+ T cell TCR signaling kinetics via the negative regulator Sprouty1
Recipient
University of Colorado Anschutz Medical Campus
Award Amount
$38,798.00
Ceiling
$38,798.00
Awarded
May 20, 2026
Identifier
1F31AI200278-01
Research project awarded to study the role of ITK in CD8+ T cell TCR signaling kinetics via Sprouty1, aiming to advance immunotherapy development and scientific leadership.
Description
The project focuses on T cell receptor signaling, immune regulation, and immunotherapy development. The research involves molecular mechanisms downstream of ITK, Sprouty1 expression, and TCR signal termination. Conducted at the University of Colorado Anschutz Medical Campus. The project aims to identify targets for therapeutic tuning of TCR signaling. Emphasizes development in independent research, leadership, and scientific communication.