Award
National Institute of Neurological Disorders and Stroke 5R01NS143814-03
Mechanisms of Claudin-5 Regulation during Neuroinflammation
Recipient
University of South Florida
Award Amount
$400,599.00
Ceiling
$400,599.00
Awarded
July 15, 2026
Identifier
5R01NS143814-03
Research award to study the mechanisms regulating Claudin-5 in neuroinflammation to develop therapeutic targets for CNS disorders, funded by NINDS.
Description
The project focuses on the regulation of Claudin-5 during neuroinflammation, with potential implications for CNS disorders involving blood-brain barrier dysfunction. The research involves in vivo and in vitro models, including transgenic mice and pharmacological approaches. The project aims to identify mechanisms and develop therapeutic targets for CNS disorders.