Award
National Institute of Allergy and Infectious Diseases 5R01AI174064-04
Immune Privilege, CNS Autoimmunity, and Clostridium perfringens Epsilon Toxin
Recipient
Weill Medical College of Cornell University, New York, NY, United States
Award Amount
$662,275.00
Ceiling
$662,275.00
Awarded
May 28, 2026
Identifier
5R01AI174064-04
Research grant to study how Clostridium perfringens epsilon toxin and Bordetella pertussis toxin disrupt CNS immune privilege to trigger autoimmunity, aiming to identify environmental triggers of Multiple Sclerosis and develop new therapeutic targets.
Description
This NIH grant supports research on the mechanisms of CNS autoimmunity related to Multiple Sclerosis, focusing on the role of bacterial toxins and immune barrier disruption. The project involves advanced molecular and cellular techniques and aims to identify new therapeutic targets.