Award

National Eye Institute 5R01EY034497-04

Elucidating the Role of Very-long-chain Polyunsaturated Fatty Acids in Retinal Health and Disease

Recipient

University of Utah

Award Amount

$390,875.00

Ceiling

$390,875.00

Awarded

July 22, 2026

Identifier

5R01EY034497-04

NIH awarded a grant to the University of Utah to study the role of VLC-PUFAs in retinal health and disease, aiming to develop synthetic lipids for therapeutic use in AMD and Stargardt's disease.

Description

This NIH-funded project focuses on lipid research related to retinal diseases, with potential therapeutic applications involving synthetic lipids for age-related macular degeneration (AMD) and Stargardt's disease. The project aims to develop synthetic very long-chain polyunsaturated fatty acids (VLC-PUFAs), test their targeting to the retina, and evaluate their functional benefits in animal models. It explores mechanisms underlying VLC-PUFA's protective effects in retinal health.

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