Award
National Heart, Lung, and Blood Institute 5R01HL109448-12
PET Imaging of Thrombus
Recipient
Massachusetts General Hospital, Boston, MA, United States
Award Amount
$806,657.00
Ceiling
$806,657.00
Awarded
February 20, 2025
Identifier
5R01HL109448-12
A research project funded by NHLBI to develop and validate PET-CT imaging using 64Cu-FBP8 for detecting thrombi in stroke patients, aiming to improve stroke diagnosis and prevention.
Description
This project aims to utilize PET-CT imaging with a novel fibrin-binding probe, 64Cu-FBP8, to detect thrombi and identify embolic sources in patients with acute stroke. The research involves validation of the probe's ability to detect thrombi in hospitalized patients, including those with acute stroke of known and unknown origins. The study will provide insights into stroke pathogenesis and lay the groundwork for improved prevention and management strategies.