Award
National Institute of Allergy and Infectious Diseases 5R01AI165510-03
Serine/threonine kinase signaling in beta-lactam resistance of Staphylococcus aureus
Recipient
University of Maryland Baltimore
Award Amount
$669,744.00
Ceiling
$669,744.00
Awarded
August 13, 2025
Identifier
5R01AI165510-03
This award funds research on the signaling pathways involved in broad-spectrum β-lactam resistance in MRSA, aiming to improve treatment options by understanding resistance mechanisms.
Description
Research project to decipher the mechanisms through which eukaryotic-like serine/threonine kinase (eSTK) controls mecA expression, identify eSTK mediators conferring non-classical resistance, and investigate compensatory resistance mechanisms in methicillin-resistant Staphylococcus aureus (MRSA).