Award
NIH Reporter #5R01AR081835-04
A Multisystem Resilience Approach in the Assessment of Postsurgical Pain Trajectories
Recipient
University of Florida, Gainesville, FL, United States
Award Amount
$594,622.00
Ceiling
$594,622.00
Awarded
June 30, 2026
Identifier
5R01AR081835-04
This award funds a research project to study multisystem resilience profiles that predict recovery from postsurgical pain in adults undergoing knee and hip arthroplasty, aiming to improve therapeutic approaches.
Description
The project aims to identify multisystem phenotypic profiles of resilience that predict postsurgical recovery trajectories in pain impact and physical function among adults undergoing knee and hip arthroplasty. It involves 300 patients aged 18+ years with assessments at baseline and five postsurgical time points over 9 months, covering demographic, health, biological, behavioral, psychological, and sociological domains. The findings may advance understanding of phenotypic mechanisms underlying postsurgical pain and inform therapeutic development to promote recovery and reduce pain burden.