Award
NIH Reporter #7R01CA276846-04
Preventing invasive prostate cancer
Recipient
State University of New York, Stony Brook
Award Amount
$1,497,888.00
Ceiling
$1,497,888.00
Awarded
September 01, 2026
Identifier
7R01CA276846-04
NIH grant awarded to State University of New York, Stony Brook for research on preventing invasive prostate cancer by inhibiting cell motility using the agent KBU2046.
Description
This project focuses on developing a novel agent, KBU2046, to inhibit cell motility as a strategy for cancer prevention and interception, with potential applications across various cancer types. The project aims to identify and validate the pharmacologic binding site of KBU2046, characterize the signaling pathway by which Raf1 regulates prostate cell motility, and evaluate targeting motility in relevant models of human disease.