# NIH Reporter #1R21AR087081-01A1

Efficacy of Sustained Anti-inflammatory Delivery in a Naturally Occurring Cruciate Ligament Injury Model

**Recipient:** University of Pennsylvania

**Award Amount:** $389,737.00
**Ceiling:** $389,737.00

**Awarded:** September 08, 2026

**Identifier:** 1R21AR087081-01A1

The University of Pennsylvania received NIH funding to study sustained delivery of anti-inflammatory agents for cruciate ligament injuries in dogs, evaluating safety, efficacy, and postoperative recovery.

### Description

Project to develop and evaluate mechanically activated microcapsules delivering sustained anti-inflammatory treatment in dogs with naturally occurring cruciate ligament injury, comparing the delivery system with injections of unencapsulated factors.

[View original record](https://reporter.nih.gov/search/J7l2tQ4hHkqRePwGq3m5kA/project-details/11454481)