Award
NIH Reporter #3R01AI169893-04S1
Reprogramming of tissue structural cells by cutaneous CD4+ T cells
Recipient
Benaroya Research Institute at Virginia Mason, Seattle, WA, United States
Award Amount
$174,987.00
Ceiling
$174,987.00
Awarded
May 25, 2026
Identifier
3R01AI169893-04S1
NIH grant awarded to study the role of cutaneous CD4+ T cells in reprogramming tissue structural cells to understand and develop therapies for inflammatory skin diseases.
Description
This NIH research grant focuses on investigating how T cells influence inflammatory memory in the skin by examining the cross-talk between T cell-derived cytokines and structural cells in vitro, in a murine model, and in patient samples. The goal is to understand the reprogramming of keratinocytes and fibroblasts during inflammation and to identify therapeutic targets to block cutaneous inflammation.