# NIH Reporter #1R01DE036079-01

An innervated TMJ-on-a-chip

**Recipient:** University of Pittsburgh at Pittsburgh

**Award Amount:** $783,258.00
**Ceiling:** $783,258.00

**Awarded:** September 16, 2026

**Identifier:** 1R01DE036079-01

Award to develop a human iPSC-based innervated TMJ microphysiological system to study pain mechanisms in temporomandibular disorders, emphasizing sex differences and personalized medicine.

### Description

This project aims to develop a human iPSC-based innervated TMJ microphysiological system (MPS) to study mechanisms of pain in temporomandibular disorders (TMDs), with a focus on sex differences and personalized medicine approaches.

[View original record](https://reporter.nih.gov/search/IgE1H2ioLUOz0qmA4MDg0Q/project-details/11385177)