Award
NIH Reporter #1R01AA031477-01A1
Insula-BNST Circuit Regulation of AUD
Recipient
Samuel Centanni
Award Amount
$2,552,568.00
Ceiling
$2,552,568.00
Awarded
September 03, 2025
Identifier
1R01AA031477-01A1
Research project funded by the National Institute on Alcohol Abuse and Alcoholism to study the insula-BNST circuit's role in alcohol use disorder, using mouse models and RNA sequencing to understand neuroadaptations related to stress and binge drinking.
Description
This project aims to investigate the neurocircuitry involved in alcohol use disorder (AUD), focusing on the insula-BNST pathway. The study will examine stress-induced neuroadaptations and their relationship to binge drinking and hyperkatifeia during abstinence, using mouse models and RNA sequencing.