Award
NIH Reporter #1K08HL183767-01
Role of Surfactant Protein A and Receptor SP-R210 Signaling in Bronchopulmonary Dysplasia.
Recipient
Pennsylvania State University Hershey Medical Center
Award Amount
$178,092.00
Ceiling
$178,092.00
Awarded
August 25, 2026
Identifier
1K08HL183767-01
The award supports research on the role of surfactant protein A and its receptor SP-R210 in the development of bronchopulmonary dysplasia in premature infants, aiming to develop new therapeutic strategies.
Description
This project aims to define the role of surfactant protein A (SP-A) and its macrophage receptor SP-R210 in alveolar macrophages mediated bronchopulmonary dysplasia (BPD) injury and elucidate mechanisms of SP-A/SP-R210-regulated intercellular crosstalk by studying extracellular vesicle uptake. The goal is to develop novel strategies to treat BPD and improve health outcomes of premature infants.