National Institute of Neurological Disorders and Stroke 1R01NS143970-01A1

Sensory-motor transformations in a neural circuit for object-directed walking

NIH grant awarded to Max Planck Florida Corporation to study neural circuits involved in sensory-motor transformations for object-directed walking, aiming to understand mechanisms relevant to mobility disorders.

Description

This study will address how appropriate brain output pathways are engaged by sensory inputs to direct the walking pattern of an animal towards a desired object. By taking a synaptic resolution view of how information is transformed across neural circuits to guide movement, this work will provide a mechanistic understanding of vital sensory-motor transformations, relevant across species. Discovering general principles underlying these transformations has the potential to accelerate our understanding and treatments for mobility disorders.

View original record