Award
National Heart, Lung, and Blood Institute 1K08HL179453-01
Carbonic Anhydrase Mediated Regulation of Microtubule Dynamics and Infection in Cystic Fibrosis
Recipient
LURIE CHILDREN'S HOSPITAL OF CHICAGO, CHICAGO, IL, UNITED STATES
Award Amount
$163,080.00
Ceiling
$163,080.00
Awarded
September 10, 2025
Identifier
1K08HL179453-01
Research project funded by NHLBI to study the role of carbonic anhydrase in microtubule dynamics and infection in cystic fibrosis, aiming to identify new therapeutic targets.
Description
This study explores how disrupted microtubule dynamics and intracellular transport, mediated by reduced carbonic anhydrase activity, contribute to increased infections in cystic fibrosis (CF). The research aims to understand these mechanisms to reveal new therapeutic targets to prevent and treat infection in people with CF and other airway diseases.