Award

National Cancer Institute PAR-24-085

Optimization of an active mutant KRAS peptide vaccine in colorectal cancer

Recipient

Johns Hopkins University

Awarded

January 16, 2026

Identifier

PAR-24-085

NIH grant awarded to Johns Hopkins University for research on KRAS peptide vaccine optimization in colorectal cancer, focusing on clinical and preclinical studies.

Description

This NIH grant supports research on KRAS-targeted vaccines and immunotherapy for colorectal cancer, including clinical trials and preclinical studies. The project involves multiple aims including clinical response evaluation, immunogenicity, and combination therapies with immune checkpoint inhibitors and KRAS signaling inhibitors.

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