Award
NIH Reporter #5R01HD108467-06
Immunologic and Predictive Features of MIS-C
Recipient
Columbia University Health Sciences
Award Amount
$503,349.00
Ceiling
$503,349.00
Awarded
August 07, 2026
Identifier
5R01HD108467-06
NIH grant awarded to Columbia University Health Sciences to study immunologic and predictive features of MIS-C using advanced immunological mapping and machine learning to improve diagnosis and prognosis.
Description
This project aims to evaluate three independent cohorts of MIS-C during acute and convalescent phases at clinical, genetic, and immunologic levels using advanced technology. The goal is to perform systemic immunological mapping and utilize machine learning algorithms to predict, diagnose, and stratify outcomes of MIS-C. The research anticipates discovering immunologic and genetic features that can aid in risk assessment, diagnosis, and prognosis, ultimately illuminating the syndrome's pathogenesis and providing actionable biomarkers.