Award
National Institute of Neurological Disorders and Stroke 5R01NS136041-03
The effects of HIV-associated extracellular vesicles on mitochondrial dysfunction in brain microvessels
Recipient
Tulane University of Louisiana
Award Amount
$475,649.00
Ceiling
$475,649.00
Awarded
June 19, 2026
Identifier
5R01NS136041-03
This award funds research on how HIV-associated extracellular vesicles cause mitochondrial dysfunction in brain microvessels, contributing to neurocognitive disorders, and investigates potential therapeutic effects of mesenchymal stem cell-derived extracellular vesicles.
Description
The project aims to elucidate the role of extracellular vesicles in HIV-associated neurocognitive disorders. It explores mitochondrial dysfunction in brain microvessels and potential therapeutic effects of MSC-derived EVs. The research is highly relevant to NIH's focus on vascular contributions to cognitive impairment and dementia.