Award
National Institute of Allergy and Infectious Diseases 5R21AI190212-02
Mechanisms of central nervous system invasion by the Lyme disease spirochete, Borrelia burgdorferi
Recipient
University of South Alabama, Mobile, AL
Award Amount
$192,500.00
Ceiling
$192,500.00
Awarded
April 01, 2026
Identifier
5R21AI190212-02
Research grant awarded to study how Lyme disease bacteria invade the central nervous system and the immune responses involved, using a murine model to aid in developing new treatments.
Description
The study aims to identify key mechanisms of Borrelia burgdorferi central nervous system invasion and host immune responses using a mouse model of Lyme disease, to inform development of novel prophylactics and therapeutics.