Award
National Institute of Neurological Disorders and Stroke 5R00NS121511-05
Elucidating the role of RNA oxidation on amyotrophic lateral sclerosis onset and progression
Recipient
University of California, San Diego, La Jolla, CA
Award Amount
$379,337.00
Ceiling
$379,337.00
Awarded
December 29, 2025
Identifier
5R00NS121511-05
This award supports research to understand how RNA oxidation contributes to ALS onset and progression, aiming to develop early diagnostic and therapeutic strategies.
Description
A growing body of evidence implicates oxidative stress in Amyotrophic Lateral Sclerosis (ALS). The project aims to identify the effects of RNA oxidation on RNA processing and neuronal death mechanisms, with the goal of developing early diagnostic and intervention strategies.