Award
National Institute of Neurological Disorders and Stroke 5R01NS113822-05
Role of ER Stress and Fatty Acid Metabolism in Glioma Stem Cells
Recipient
Massachusetts General Hospital
Award Amount
$381,716.00
Ceiling
$381,716.00
Awarded
July 15, 2024
Identifier
5R01NS113822-05
NIH awarded a research grant to Massachusetts General Hospital to study ER stress and fatty acid metabolism in glioma stem cells to develop targeted therapies for glioblastoma.
Description
This NIH grant project focuses on glioblastoma research, specifically investigating the role of endoplasmic reticulum (ER) stress and fatty acid metabolism in glioma stem cells (GSCs). The project aims to elucidate mechanisms supporting GSC self-renewal and tumorigenicity and to develop targeted therapies using patient-derived GSC mouse models.