Award
National Institute of Dental and Craniofacial Research 5R01DE033986-02
ARID1 proteins orchestrate cranial neural crest differentiation
Recipient
Cincinnati Children's Hospital Medical Center
Awarded
April 09, 2026
Identifier
5R01DE033986-02
Research project focused on the role of ARID1 proteins in craniofacial development and neural crest differentiation, funded by NIDCR.
Description
This project aims to study the role of ARID1A and ARID1B in craniofacial development and neural crest cell differentiation, with potential implications for Coffin-Siris Syndrome. The research involves chromatin remodeling, gene regulation, and signaling pathways such as Wnt and Hedgehog. The project is funded by the National Institute of Dental and Craniofacial Research (NIDCR).