Award
National Cancer Institute 5F31CA288070-02
Regulation of the retinoblastoma (Rb) tumor suppressor by the ubiquitin-proteasome system
Recipient
University of North Carolina at Chapel Hill, Department of Pharmacology
Award Amount
$40,752.00
Ceiling
$40,752.00
Awarded
July 24, 2025
Identifier
5F31CA288070-02
The award supports research on how the ubiquitin-proteasome system regulates the retinoblastoma (Rb) tumor suppressor protein, affecting cell cycle progression and response to Cdk4/6 inhibitors in breast cancer.
Description
This project investigates the ubiquitin-mediated degradation of the Rb tumor suppressor and its role in cell cycle regulation and response to Cdk4/6 inhibitors in breast cancer.