Award
National Cancer Institute 5U01CA272610-04
Elucidating and Targeting tumor dependencies and drug resistance determinants at the single cell level
Recipient
Columbia University Health Sciences
Award Amount
$967,866.00
Ceiling
$967,866.00
Awarded
August 15, 2025
Identifier
5U01CA272610-04
NIH grant awarded to Columbia University Health Sciences for research on tumor dependencies and drug resistance at the single cell level, with a funding amount of approximately $967,866 for FY 2025.
Description
The project focuses on the pharmacological targeting of Master Regulator proteins and Tumor Checkpoint modules at the single-cell level. The research aims to develop combination therapies and understand mechanisms of drug resistance. The project involves analysis of multiple tumor subtypes and has led to the development of clinical tests (OncoTarget and OncoTreat).