Award
National Institute of General Medical Sciences 5R35GM142438-05
Learning about the evolution of structural variations from genomic and transcriptomic data
Recipient
Florida Atlantic University, Boca Raton, FL
Award Amount
$373,597.00
Ceiling
$373,597.00
Awarded
June 05, 2025
Identifier
5R35GM142438-05
The award supports research developing statistical and machine learning methods to study the evolution of structural variations in genomes, with applications to multiple species including humans. It aims to improve understanding of evolutionary outcomes and parameters of structural variations.
Description
This project aims to develop advanced statistical and machine learning models to better understand structural variations and their role in evolution and disease across multiple species. The research focuses on computational and statistical approaches to study the evolution of structural variations such as gene duplication, deletion, inversion, and translocation using genomic and transcriptomic data. The project will implement new methods in open source software and apply them to humans and other taxa.