# NIH Reporter #1F31AR088336-01

Uncovering Architectural Features in Hyper-Adhesive Desmosomes

**Recipient:** University of Alabama at Birmingham

**Award Amount:** $42,036.00
**Ceiling:** $42,036.00

**Awarded:** September 11, 2026

**Identifier:** 1F31AR088336-01

The project studies the nanoscale architecture of desmoplakin in calcium-dependent and hyper-adhesive desmosomes, including how disease-associated variants affect cell adhesion and tissue differentiation.

### Description

Research project examining how desmoplakin architecture changes in hyper-adhesive desmosomes and how those changes affect desmosome function and disease-associated variants.

[View original record](https://reporter.nih.gov/search/J7l2tQ4hHkqRePwGq3m5kA/project-details/11458564)