Award
National Institute on Deafness and Other Communication Disorders 1R21DC023703-01
Effects of early sensory loss on the developing auditory thalamocortical circuit
Recipient
Johns Hopkins University
Award Amount
$194,270.00
Ceiling
$194,270.00
Awarded
May 14, 2026
Identifier
1R21DC023703-01
Research project funded by the National Institute on Deafness and Other Communication Disorders to study the development and rewiring of the auditory thalamocortical circuit in cases of early sensory loss, aiming to inform therapeutic interventions for hearing deficits.
Description
The project aims to expand understanding of auditory thalamocortical circuitry and explore neurobiological mechanisms underlying hearing deficits at the thalamocortical level. It involves studying the developmental trajectory of the auditory thalamocortical circuit anatomically and functionally, investigating changes in deafness using transgenic mice and genetically modified viruses, and mapping auditory circuit development to guide effective treatments.