Award
NIH Reporter #BX-21-023
The Tumor Immune Microenvironment in Pancreatic Cancer Chemoresistance
Recipient
Not specified
Awarded
December 01, 2025
Identifier
BX-21-023
Research project focused on understanding chemoresistance in pancreatic cancer using advanced molecular techniques to develop targeted therapies for veterans.
Description
This project aims to uncover mechanisms of chemoresistance in pancreatic ductal adenocarcinoma (PDAC) utilizing single-cell RNA sequencing, patient-derived organoid culture, and biospecimen acquisition. It involves developing a comprehensive dataset of longitudinal tumor samples and in vitro co-culture systems to identify therapeutic targets and build a precision medicine platform for veterans.