Award
NIH Reporter #1R21AG085470-01A1
Dissecting the interaction between sex and APOE genotype in modulating AD risk
Recipient
Arizona State University - Tempe Campus, Scottsdale, AZ
Award Amount
$431,750.00
Ceiling
$431,750.00
Awarded
September 02, 2024
Identifier
1R21AG085470-01A1
A multiyear NIH grant awarded to study how sex and APOE genotype interact to affect Alzheimer's Disease risk using stem cell models.
Description
This project aims to use human-induced pluripotent stem cell (hiPSC)-based models to elucidate the relationship between APOE isoforms, biological sex, and Alzheimer's Disease (AD) risk, advancing understanding of the genetic interactions that influence AD onset and progression.