# NIH Reporter #1F32DK148022-01

Functional and Molecular Dissection of Vagal Mechanosensory Neurons Regulating Feeding and Gastrointestinal Physiology

**Recipient:** Monell Chemical Senses Center

**Award Amount:** $76,780.00
**Ceiling:** $76,780.00

**Awarded:** May 22, 2026

**Identifier:** 1F32DK148022-01

The project examines how Piezo2- and TRPA1-expressing vagal neurons sense stomach stretch and influence food intake and physiological responses, using genetic ablation, behavioral assays, in vivo calcium imaging, and spatial transcriptomics.

### Description

NIH research project investigating how vagal afferent neuron subtypes detect gastric distension and regulate feeding and gastrointestinal physiology.

[View original record](https://reporter.nih.gov/search/47CiHD0bJ0u2LtDABS0zbg/project-details/11388382)