Award
NIH Reporter #5R00AG073455-06
Mutant Tubulins Confer Resistance to Pathological Tau
Recipient
Seattle Institute for Biomedical/Clinical Research
Award Amount
$249,000.00
Ceiling
$249,000.00
Awarded
July 10, 2026
Identifier
5R00AG073455-06
NIH grant awarded to study how mutant tubulin affects tau pathology in neurodegenerative diseases, aiming to understand disease mechanisms and develop therapies.
Description
This NIH research grant focuses on studying the mechanisms by which mutant tubulin suppresses tau pathology, which is relevant to neurodegenerative diseases such as Alzheimer's Disease. The project uses C. elegans, in vitro systems, and mammalian neurons to elucidate these mechanisms and aims to contribute to understanding neurodegenerative disease mechanisms and potentially new therapeutic strategies.