Award
Eunice Kennedy Shriver National Institute of Child Health and Human Development 5R01HD088571-10
Comparative studies on the regulation of metabolism during sperm capacitation
Recipient
WEILL MEDICAL COLL OF CORNELL UNIV, NEW YORK, NY, UNITED STATES
Award Amount
$686,583.00
Ceiling
$686,583.00
Awarded
May 12, 2026
Identifier
5R01HD088571-10
A research project funded by NICHD to study metabolic regulation during sperm capacitation, investigating how sperm utilize nutrients and the role of soluble adenylyl cyclase in these processes.
Description
This project aims to apply metabolite profiling and flux analyses to understand how sperm regulate their metabolic pathways and utilize nutrients during maturation. The role of soluble adenylyl cyclase (sAC) in these metabolic changes will be investigated. It focuses on reproductive biology and sperm metabolism, elucidating metabolic regulation during sperm capacitation critical for fertilization.